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Article

Detection of Altered Global DNA Methylation in Coronary Artery Disease Patients

1 Jul 2008

Abstract excerpt

Epigenetic modifications, especially alteration in DNA methylation, are increasingly being recognized as a key factor in the pathogenesis of complex disorders, including atherosclerosis. However, there are limited data on the epigenetic changes in the coronary artery disease (CAD) patients. In the present study we evaluated the methylation status of genomic DNA from peripheral lymphocytes in a cohort of 287...

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PMID: 18613790
DOI: 10.1089/dna.2007.0694

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