Article
DNMT3a rs1550117 polymorphism association with increased risk of Helicobacter pylori infection.
Asian Pacific journal of cancer prevention : APJCP - 1 Jan 2013
Cao Xue-Yuan, Jia Zhi-Fang, Cao Dong-Hui, Kong Fei, Jin Mei-Shan, Suo Jian, Jiang Jing
Abstract excerpt
BACKGROUND: DNA methyltransferase-3a (DNMT3a) plays significant roles in embryogenesis and the generation of aberrant methylation in carcinogenesis. This study aimed to investigate associations between single nucleotide polymorphisms (SNPs) of the DNMT3a gene and risk of Helicobacter pylori infection, gastric atrophy and gastric cancer. METHODS: The subjects comprised 447 patients with gastric cancer; 111...
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