Effect of DNMT3A polymorphisms on CpG island hypermethylation in gastric mucosa.

doi:10.1186/s12881-020-01142-7

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

Effect of DNMT3A polymorphisms on CpG island hypermethylation in gastric mucosa.

BMC medical genetics - 16 Oct 2020

Takano Hikaru, Shibata Tomoyuki, Nakamura Masakatsu, Sakurai Naoko, Hayashi Tasuku, Ota Masafumi, Nomura-Horita Tomoe, Hayashi Ranji, Shimasaki Takeo, Otsuka Toshimi, Tahara Tomomitsu, Arisawa Tomiyasu

Abstract excerpt

BACKGROUND: CpG methylation of tumor suppressor genes occurs in the early stage of carcinogenesis. Detecting risk factors for aberrant CpG methylation is clinically important for predicting cancer development. DNA methyltransferase (DNMT) 3a is considered to play critical roles in the DNA methylation process during pathogenesis. In this study, we evaluated the association between DNMT3A polymorphisms (rs6733868...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to CpG Islands

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cyclin-Dependent Kinase Inhibitor p16

Share to Death-Associated Protein Kinases

Share to DNA (Cytosine-5-)-Methyltransferases

Share to DNA Methyltransferase 3A

Share to Gastric Mucosa

Share to Helicobacter Infections

Share to Helicobacter pylori

Source

Open in PubMed Open full text

Identifiers

PMID: 33066747
DOI: 10.1186/s12881-020-01142-7
PMCID: PMC7562764

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Effect of DNMT3A polymorphisms on CpG island hypermethylation in gastric mucosa.PMID 33066747Read ↗

DNMT3a rs1550117 polymorphism association with increased risk of Helicobacter pylori infection.Semantic proximity Read ↗

DNMT1, DNMT3A and DNMT3B Polymorphisms Associated With Gastric Cancer Risk: A Systematic Review and Meta-analysis.Semantic proximity Read ↗

An updated meta-analysis investigating the association between DNMTs gene polymorphism andgastric cancer risk.Semantic proximity Read ↗

Polymorphisms of the DNA methyltransferase 1 associated with reduced risks of Helicobacter pylori infection and increased risks of gastric atrophy.Semantic proximity Read ↗

CpG island methylator phenotype and Helicobacter pylori infection associated with gastric cancer.Semantic proximity Read ↗

DNA methyltransferase 3a rs1550117 genetic polymorphism predicts poor survival in gastric cancer patients.Semantic proximity Read ↗

A functional polymorphism in the DNA methyltransferase-3A promoter modifies the susceptibility in gastric cancer but not in esophageal carcinoma.Semantic proximity Read ↗

Clinical significance of the expression of DNA methyltransferase proteins in gastric cancerSemantic proximity Read ↗

Association of five genetic variations in DNMT1 and DNMT3A with gastric cancer in a Chinese population.Semantic proximity Read ↗

CpG Island Hypermethylation of Tumor‐Suppressor Genes in H. pylori‐Infected Non‐Neoplastic Gastric Mucosa Is Linked with Gastric Cancer RiskSemantic proximity Read ↗

Effect of polymorphisms of IL-17A, -17F and MIF genes on CpG island hyper-methylation (CIHM) in the human gastric mucosa.Semantic proximity Read ↗

Polymorphism of DNA Methyltransferase 3b and Association with Development and Prognosis in Gastric Cancer.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.