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Article

Polymorphisms of the DNA methyltransferase 1 associated with reduced risks of Helicobacter pylori infection and increased risks of gastric atrophy.

PloS one - 1 Jan 2012

Jiang Jing, Jia Zhifang, Cao Donghui, Jin Mei-Shan, Kong Fei, Suo Jian, Cao Xueyuan

Abstract excerpt

INTRODUCTION: DNA methyltransferase-1(DNMT1) is an important enzyme in determining genomic methylation patterns in mammalian cells. We investigated the associations between SNPs in the DNMT1 gene and risks of developing H. pylori seropositivity, gastric atrophy and gastric cancer in the Chinese population. METHODS: The study consisted of 447 patients with gastric cancer; 111 patients with gastric atrophy; and 961...

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Source

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Identifiers

PMID: 23049933
DOI: 10.1371/journal.pone.0046058
PMCID: PMC3457938

Genes

DNMT1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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