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Performance of Idylla KRAS assay on extracted DNA and de-stained cytology smears: Can we rescue small sample?

Annals of diagnostic pathology - 1 Oct 2022

Wei Qing, Eltoum Isam A, Mackinnon Alexander Craig, Harada Shuko

Abstract excerpt

OBJECTIVE: KRAS is a frequently mutated gene in cancers, and with recent FDA-approved targeted therapy for the G12C mutation, testing for KRAS variants is essential. We evaluated the performance of the Idylla KRAS assay on extracted DNA and cytology smears in order to expand the utility of the assay. METHODS: In total, fifty-seven human samples were analyzed. Idylla results from sixteen DNA extracted from...

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PMID: 35961282
DOI: 10.1016/j.anndiagpath.2022.152023

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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