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Article

KRAS mutation testing in clinical practice.

Expert review of molecular diagnostics - 1 Mar 2015

Perincheri Sudhir, Hui Pei

Abstract excerpt

Activating mutation of KRAS plays a significant role in the pathogenesis of common human malignancies and molecular testing of KRAS mutation has emerged as an essential biomarker in the current practice of clinical oncology. The presence of KRAS mutation is generally associated with clinical aggressiveness of the cancer and reduced survival of the patient. Therapeutically, KRAS mutation testing has maximum...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 25487540
DOI: 10.1586/14737159.2015.986102

Genes

KRAS

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