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Detection of mutated KRAS, TP53, CDK2A, and SMAD4 in tumor cell-free DNA of Brazilian pancreatic adenocarcinoma patients using next-generation sequencing

2025-01-28

Abstract excerpt

<title>Abstract</title> <p>Pancreatic adenocarcinoma (PDAC) is one of the most lethal cancer types worldwide, with early diagnosis being challenging due to nonspecific symptoms that are often noticed only when the tumor reaches a large size. Liquid biopsy has emerged as a promising technology for cancer detection, where the identification of tumoral cell-free DNA (cfDNA) using sensitive methodologies can identify...

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Literature Corpus work
10c027c2-4eab-5efa-a215-fad0e21364d9
DOI
10.21203/rs.3.rs-5850874/v1
Open publication

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Detection of mutated KRAS, TP53, CDK2A, and SMAD4 in tumor cell-free DNA of Brazilian pancreatic adenocarcinoma patients using next-generation sequencingDOI 10.21203/rs.3.rs-5850874/v1
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