Article
Precision neuro-oncology: a pilot analysis of personalized treatment in recurrent glioma.
Journal of cancer research and clinical oncology - 1 Jul 2023
Lazaridis Lazaros, Schmidt Teresa, Oster Christoph, Blau Tobias, Pierscianek Daniela, Siveke Jens T, Bauer Sebastian, Schildhaus Hans-Ulrich, Sure Ulrich, Keyvani Kathy, Kleinschnitz Christoph, Stuschke Martin, Herrmann Ken, Deuschl Cornelius, Scheffler Björn, Kebir Sied, Glas Martin
Abstract excerpt
PURPOSE: When brain cancer relapses, treatment options are scarce. The use of molecularly matched targeted therapies may provide a feasible and efficacious way to treat individual patients based on the molecular tumor profile. Since little information is available on this strategy in neuro-oncology, we retrospectively analyzed the clinical course of 41 patients who underwent advanced molecular testing at disease...
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