Article
Molecular matched targeted therapies for primary brain tumors-a single center retrospective analysis.
Journal of neuro-oncology - 1 Sept 2022
Luger Anna-Luisa, König Sven, Samp Patrick Felix, Urban Hans, Divé Iris, Burger Michael C, Voss Martin, Franz Kea, Fokas Emmanouil, Filipski Katharina, Demes Melanie-Christin, Stenzinger Albrecht, Sahm Felix, Reuss David E, Harter Patrick N, Wagner Sebastian, Hattingen Elke, Wichert Jennifer, Lapa Constantin, Fröhling Stefan, Steinbach Joachim P, Ronellenfitsch Michael W
Abstract excerpt
PURPOSE: Molecular diagnostics including next generation gene sequencing are increasingly used to determine options for individualized therapies in brain tumor patients. We aimed to evaluate the decision-making process of molecular targeted therapies and analyze data on tolerability as well as signals for efficacy. METHODS: Via retrospective analysis, we identified primary brain tumor patients who were treated...
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