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TRIM family proteins: roles in proteostasis and neurodegenerative diseases

1 Aug 2022

Abstract excerpt

Neurodegenerative diseases (NDs) are a diverse group of disorders characterized by the progressive degeneration of the structure and function of the central or peripheral nervous systems. One of the major features of NDs, such as Alzheimer's disease (AD), Parkinson's disease (PD) and Huntington's disease (HD), is the aggregation of specific misfolded proteins, which induces cellular dysfunction, neuronal death,...

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PMID: 35946309
DOI: 10.1098/rsob.220098

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