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Protein modification in neurodegenerative diseases

1 Aug 2024

Abstract excerpt

Posttranslational modifications play a crucial role in governing cellular functions and protein behavior. Researchers have implicated dysregulated posttranslational modifications in protein misfolding, which results in cytotoxicity, particularly in neurodegenerative diseases such as Alzheimer disease, Parkinson disease, and Huntington disease. These aberrant posttranslational modifications cause proteins to...

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PMID: 39105197
DOI: 10.1002/mco2.674

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