Article
TRIM proteins and diseases.
Journal of biochemistry - 1 Feb 2017
Watanabe Masashi, Hatakeyama Shigetsugu
Abstract excerpt
Ubiquitination is one of the posttranslational modifications that regulates a number of intracellular events including signal transduction, protein quality control, transcription, cell cycle, apoptosis and development. The ubiquitin system functions as a garbage machine to degrade target proteins and as a regulator for several signalling pathways. Biochemical reaction of ubiquitination requires several enzymes...
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