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Role of autophagy and proteostasis in neurodegenerative diseases: Exploring the therapeutic interventions

1 Apr 2024

Abstract excerpt

Neurodegenerative disorders are devastating disorders characterized by gradual loss of neurons and cognition or mobility impairment. The common pathological features of these diseases are associated with the accumulation of misfolded or aggregation of proteins. The pivotal roles of autophagy and proteostasis in maintaining cellular health and preventing the accumulation of misfolded proteins, which are associated...

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PMID: 38570333
DOI: 10.1111/cbdd.14515

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