Article
A novel high-risk subpopulation identified by CTSL and ZBTB7B in gastric cancer.
British journal of cancer - 1 Nov 2022
Cui Kaisa, Yao Surui, Liu Bingxin, Sun Shengbai, Gong Liang, Li Qilin, Fei Bojian, Huang Zhaohui
Abstract excerpt
BACKGROUND: Gastric cancer (GC) is characterised by a heterogeneous tumour microenvironment (TME) that is closely associated with the response to treatment, especially immunotherapies. However, most previous GC molecular subtyping systems need complex gene signatures and examination methods, restricting their clinical applications. Thus, we developed a new TME-based molecular subtype using only two genes....
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