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Characterization of the crotonylation landscape in gastric cancer: a machine learning-derived prognostic signature and the oncogenic role of TIMP1

2026-07-28

Abstract excerpt

Gastric cancer (GC) remains a lethal malignancy with high heterogeneity and poor prognosis. Crotonylation, a key post-translational modification, contributes significantly to oncogenic processes and immune system interactions; however, its prognostic significance in gastric cancer is not fully understood. We integrated single-cell RNA sequencing and bulk transcriptomics to evaluate cell-specific crotonylation acti...

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Literature Corpus work
c6458411-3b69-5928-8246-d6d290189005
DOI
10.1186/s40246-026-01018-6
Open publication

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Characterization of the crotonylation landscape in gastric cancer: a machine learning-derived prognostic signature and the oncogenic role of TIMP1DOI 10.1186/s40246-026-01018-6
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