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Article

Comprehensive analysis of tumor mutation burden and immune microenvironment in gastric cancer.

Bioscience reports - 26 Feb 2021

Yu Jie, Zhang QianYun, Wang MengChuan, Liang SiJia, Huang HongYun, Xie Lang, Cui ChunHui, Yu JinLong

Abstract excerpt

Tumor mutation burden (TMB) was a promising marker for immunotherapy. We aimed to investigate the prognostic role of TMB and its relationship with immune cells infiltration in gastric cancer (GC). We analyzed the mutation landscape of all GC cases and TMB of each GC patient was calculated and patients were divided into TMB-high and TMB-low group. Differentially expressed genes (DEGs) between the two groups were...

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Identifiers

PMID: 33492335
DOI: 10.1042/BSR20203336
PMCID: PMC7921293

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