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Comprehensive immunophenotyping of gastric adenocarcinoma identifies an inflamed class of tumors amenable to immunotherapies

1 Mar 2025

Abstract excerpt

Background Gastric adenocarcinoma (GAC) imposes a considerable global health burden. Molecular profiling of GAC from the tumor microenvironment perspective through a multi-omics approach is eagerly awaited in order to allow a more precise application of novel therapies in the near future. Methods To better understand the tumor-immune interface of GAC, we identified an internal cohort of 82 patients that allowed...

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PMID: 40102027
DOI: 10.1136/jitc-2024-010024

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