Gene-Based Variant Analysis of Whole-Exome Sequencing in Relation to Eosinophil Count.

Abstract excerpt

Eosinophils play important roles in the release of cytokine mediators in response to inflammation. Many associations between common genetic variants and eosinophils have already been reported, using single nucleotide polymorphism (SNP) array data. Here, we have analyzed 200,000 whole-exome sequences (WES) from the UK Biobank cohort and performed gene-based analyses of eosinophil count. We defined five different...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Eosinophils
• Share to Exome
• Share to Exome Sequencing