Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Targeting Emerging RNA Viruses by Engineered Human Superantibody to Hepatitis C Virus RNA-Dependent RNA Polymerase

22 Jul 2022

Abstract excerpt

RNA-dependent RNA polymerase (RdRp) is a unique and highly conserved enzyme across all members of the RNA virus superfamilies. Besides, humans do not have a homolog of this protein. Therefore, the RdRp is an attractive target for a broadly effective therapeutic agent against RNA viruses. In this study, a formerly generated cell-penetrating human single-chain antibody variable fragment (superantibody) to a...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Hepatitis C virus research
Share to SARS-CoV-2 and COVID-19 Research
Share to Viral Infections and Immunology Research

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 35935185
DOI: 10.3389/fmicb.2022.926929

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 9 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Targeting Emerging RNA Viruses by Engineered Human Superantibody to Hepatitis C Virus RNA-Dependent RNA PolymerasePMID 35935185Read ↗

Targeting the RdRp of Emerging RNA Viruses: The Structure-Based Drug Design ChallengeSemantic proximity Read ↗

Antiviral Therapy Targeting Viral PolymeraseSemantic proximity Read ↗

Inhibitory antibodies identify unique sites of therapeutic vulnerability in rhinovirus and other enterovirusesSemantic proximity Read ↗

The RdRp Thumb-1 Pocket is a Conserved Target for Broad-Spectrum Antiviral DevelopmentSemantic proximity Read ↗

Interference of HCV replication by cell penetrable human monoclonal scFv specific to NS5B polymerase.Semantic proximity Read ↗

A Harmless Avian Vaccine Virus Could Be Developed into an Off-the-Shelf “Antibiotic” for VirusesSemantic proximity Read ↗

A highly conserved WDYPKCDRA epitope in the RNA directed RNA polymerase of human coronaviruses can be used as epitope-based universal vaccine designSemantic proximity Read ↗

Humanized-VHH Transbodies that Inhibit HCV Protease and ReplicationSemantic proximity Read ↗

Alphavirus antivirals targeting RNA‐dependent RNA polymerase domain of nsP4 divulged using surface plasmon resonanceSemantic proximity Read ↗

1mΨ influences the performance of various positive-stranded RNA virus-based repliconsSemantic proximity Read ↗

A Conserved Inhibitory Mechanism of a Lycorine Derivative against Enterovirus and Hepatitis C Virus.Semantic proximity Read ↗

Infectious RNA vaccine protects mice against chikungunya virus infection.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.