Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A Conserved Inhibitory Mechanism of a Lycorine Derivative against Enterovirus and Hepatitis C Virus.

Antimicrobial agents and chemotherapy - 1 Feb 2016

Guo Yu, Wang Yaxin, Cao Lin, Wang Peng, Qing Jie, Zheng Qizhen, Shang Luqing, Yin Zheng, Sun Yuna

Abstract excerpt

Enterovirus 71 (EV71) (Picornaviridae family) and hepatitis C virus (HCV) (Flaviviridae family) are the causative agents of human hand, foot, and mouth disease (HFMD) and hepatitis C, resulting in a severe pandemic involving millions of infections in the Asia-Pacific region and worldwide. The great impact of EV71 and HCV on public health highlights the need to further our understanding of the biology of these two...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antiviral Agents
Share to Drug Interactions

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Drug Resistance, Viral

Share to Enterovirus A, Human

Share to Hepacivirus

Share to Structural Homology, Protein

Share to Viral Nonstructural Proteins

Share to Virus Replication

Source

Open in PubMed Open full text

Identifiers

PMID: 26596952
DOI: 10.1128/AAC.02274-15
PMCID: PMC4750679

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A Conserved Inhibitory Mechanism of a Lycorine Derivative against Enterovirus and Hepatitis C Virus.PMID 26596952Read ↗

Repurposing screen identifies novel candidates for broad-spectrum coronavirus antivirals and druggable host targetsSemantic proximity Read ↗

Inhibitory antibodies identify unique sites of therapeutic vulnerability in rhinovirus and other enterovirusesSemantic proximity Read ↗

Selective human enterovirus and rhinovirus inhibitors: An overview of capsid‐binding and protease‐inhibiting moleculesSemantic proximity Read ↗

Novel Pan-Coronavirus 3CL Protease Inhibitor MK-7845: Bio-Logical and Pharmacological ProfilingSemantic proximity Read ↗

Inhibition of early RNA replication in Chikungunya and Dengue virus by lycorine: In vitro and in silico studiesSemantic proximity Read ↗

Inhibition of enterovirus 71 replication by an α-hydroxy-nitrile derivative NK-1.9k.Semantic proximity Read ↗

Broad-spectrum virucidal activity of bacterial secreted lipases against flaviviruses, SARS-CoV-2 and other enveloped virusesSemantic proximity Read ↗

Identification of a Broadly Acting Inhibitor of the Alphavirus Non-Structural Protein 2 HelicaseSemantic proximity Read ↗

Leucoverdazyls as novel potent inhibitors of enterovirus replicationSemantic proximity Read ↗

Post-infection treatment with a protease inhibitor increases survival of mice with a fatal SARS-CoV-2 infectionSemantic proximity Read ↗

Inhibitor-induced dimerization mediates lufotrelvir resistance in mutants of SARS-CoV-2 3C-like protease.Semantic proximity Read ↗

SARS-CoV-2 3CLpro mutations T21I and E166A confer differential resistance to simnotrelvir, bofutrelvir, and ensitrelvir.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.