Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

1mΨ influences the performance of various positive-stranded RNA virus-based replicons

31 Jul 2024

Abstract excerpt

Self-amplifying RNAs (saRNAs) are versatile vaccine platforms that take advantage of a viral RNA-dependent RNA polymerase (RdRp) to amplify the messenger RNA (mRNA) of an antigen of interest encoded within the backbone of the viral genome once inside the target cell. In recent years, more saRNA vaccines have been clinically tested with the hope of reducing the vaccination dose compared to the conventional mRNA...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Mosquito-borne diseases and control
Share to RNA Interference and Gene Delivery
Share to Viral Infections and Immunology Research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 39085360
DOI: 10.1038/s41598-024-68617-y

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

1mΨ influences the performance of various positive-stranded RNA virus-based repliconsPMID 39085360Read ↗

Improvement in the potency of a N1-methylpseudouridine-modified self-amplifying RNA through mutations in the RNA-dependent RNA polymerase.Semantic proximity Read ↗

Trans-Amplifying RNA: A Journey from Alphavirus Research to Future VaccinesSemantic proximity Read ↗

Self-replicating alphavirus RNA vaccinesSemantic proximity Read ↗

Self-amplifying RNAs generated with the modified nucleotides 5-methylcytidine and 5-methyluridine mediate strong expression and immunogenicity in vivoSemantic proximity Read ↗

The Importance of RNA-Based Vaccines in the Fight against COVID-19: An OverviewSemantic proximity Read ↗

Self-Replicating RNA Viruses for Vaccine Development Against Infectious Diseases and CancerSemantic proximity Read ↗

Self-Replicating Alphaviruses: From Pathogens to Therapeutic AgentsSemantic proximity Read ↗

Self-Amplifying RNA Viruses as RNA VaccinesSemantic proximity Read ↗

Self-Amplifying RNA: A Second Revolution of mRNA Vaccines against COVID-19Semantic proximity Read ↗

Self-Replicating RNA Viruses for RNA TherapeuticsSemantic proximity Read ↗

Replicon RNA vaccines: design, delivery, and immunogenicity in infectious diseases and cancerSemantic proximity Read ↗

Vaccines’ New Era-RNA VaccineSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.