Article
Leptin mutation and mycobacterial infection lead non-synergistically to a similar metabolic syndrome.
Metabolomics : Official journal of the Metabolomic Society - 7 Aug 2022
Ding Yi, Haks Mariëlle C, van den Eeden Susan J F, Ottenhoff Tom H M, Harms Amy C, Hankemeier Thomas, Eeza Muhamed N H, Matysik Jörg, Alia A, Spaink Herman P
Abstract excerpt
INTRODUCTION: The leptin signaling pathway plays an important role as a key regulator of glucose homeostasis, metabolism control and systemic inflammatory responses. However, the metabolic effects of leptin on infectious diseases, for example tuberculosis (TB), are still little known. OBJECTIVES: In this study, we aim to investigate the role of leptin on metabolism in the absence and presence of mycobacterial...
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