Article

Glucocorticoid treatment exacerbates mycobacterial infection by reducing the phagocytic capacity of macrophages Glucocorticoids and zebrafish TB

2020-06-20

Abstract excerpt

Glucocorticoids are effective drugs for treating immune-related diseases, but prolonged therapy is associated with an increased risk of various infectious diseases, including tuberculosis. In this study, we have used a larval zebrafish model for tuberculosis, based on Mycobacterium marinum ( Mm ) infection, to study the effect of glucocorticoids. Our results show that the synthetic glucocorticoid beclomethasone...

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Literature Corpus work: 2c6604ec-370b-5f32-9fee-01315822f956
DOI: 10.1101/2020.06.19.161653

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