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Article

Highly Divergent SARS-CoV-2 Alpha Variant in Chronically Infected Immunocompromised Person.

Emerging infectious diseases - 1 Sept 2022

Munnink Bas B Oude, Nijhuis Roel H T, Worp Nathalie, Boter Marjan, Weller Babette, Verstrepen Babs E, GeurtsvanKessel Corine, Corsten Maarten F, Russcher Anne, Koopmans Marion

Abstract excerpt

We detected a highly divergent SARS-CoV-2 Alpha variant in an immunocompromised person several months after the latest detection of the Alpha variant in the Netherlands. The patient was infected for 42 weeks despite several treatment regimens and disappearance of most clinical symptoms. We identified several potential immune escape mutations in the spike protein.

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 35925013
DOI: 10.3201/eid2809.220875
PMCID: PMC9423911

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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