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SARS-CoV-2 genome surveillance in Mainz, Germany, reveals convergent origin of the N501Y spike mutation in a hospital setting

2021-02-12

Abstract excerpt

While establishing a regional SARS-Cov-2 variant surveillance by genome sequencing, we have identified three infected individuals in a clinical setting (two long-term hospitalized patients and a nurse) that shared the spike N501Y mutation within a genotype background distinct from the current viral variants of concern. We suggest that the adaptive N501Y mutation, known to increase SARS-CoV-2 transmissibility, aros...

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Literature Corpus work
e0769011-e303-5078-a592-eb20781b2d9c
DOI
10.1101/2021.02.11.21251324
Open publication

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SARS-CoV-2 genome surveillance in Mainz, Germany, reveals convergent origin of the N501Y spike mutation in a hospital settingDOI 10.1101/2021.02.11.21251324
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