Article

The mutational steps of SARS-CoV-2 to become like Omicron within seven months: the story of immune escape in an immunocompromised patient

2022-03-07

Abstract excerpt

<h4>ABSTRACT</h4> We studied a unique case of prolonged viral shedding in an immunocompromised patient that generated a series of SARS-CoV-2 immune escape mutations over a period of seven months. During the persisting SARS-CoV-2 infection seventeen non-synonymous mutations were observed, thirteen (13/17; 76.5%) of which occurred in the genomic region coding for spike. Fifteen (15/17; 88.2%) of these mutations have...

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Literature Corpus work: 32b92f66-e07d-58c8-871b-71baab2b0e67
DOI: 10.1101/2022.03.04.22271540

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