Article
A tale of two plasmids: contributions of plasmid associated phenotypes to epidemiological success among Shigella.
Proceedings. Biological sciences - 10 Aug 2022
Malaka De Silva P, Stenhouse George E, Blackwell Grace A, Bengtsson Rebecca J, Jenkins Claire, Hall James P J, Baker Kate S
Abstract excerpt
Dissemination of antimicrobial resistance (AMR) genes by horizontal gene transfer (HGT) mediated through plasmids is a major global concern. Genomic epidemiology studies have shown varying success of different AMR plasmids during outbreaks, but the underlying reasons for these differences are unclear. Here, we investigated two Shigella plasmids (pKSR100 and pAPR100) that circulated in the same transmission...
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