Article
Differential dynamics and impacts of prophages and plasmids on the pangenome and virulence factor repertoires of Shiga toxin-producing Escherichia coli O145:H28.
Microbial genomics - 1 Jan 2020
Nakamura Keiji, Murase Kazunori, Sato Mitsuhiko P, Toyoda Atsushi, Itoh Takehiko, Mainil Jacques Georges, Piérard Denis, Yoshino Shuji, Kimata Keiko, Isobe Junko, Seto Kazuko, Etoh Yoshiki, Narimatsu Hiroshi, Saito Shioko, Yatsuyanagi Jun, Lee Kenichi, Iyoda Sunao, Ohnishi Makoto, Ooka Tadasuke, Gotoh Yasuhiro, Ogura Yoshitoshi, Hayashi Tetsuya
Abstract excerpt
Phages and plasmids play important roles in bacterial evolution and diversification. Although many draft genomes have been generated, phage and plasmid genomes are usually fragmented, limiting our understanding of their dynamics. Here, we performed a systematic analysis of 239 draft genomes and 7 complete genomes of Shiga toxin (Stx)-producing Escherichia coli O145:H28, the major virulence factors of which are...
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