Article
Horizontal antimicrobial resistance transfer drives epidemics of multiple Shigella species.
Nature communications - 13 Apr 2018
Baker Kate S, Dallman Timothy J, Field Nigel, Childs Tristan, Mitchell Holly, Day Martin, Weill François-Xavier, Lefèvre Sophie, Tourdjman Mathieu, Hughes Gwenda, Jenkins Claire, Thomson Nicholas
Abstract excerpt
Horizontal gene transfer has played a role in developing the global public health crisis of antimicrobial resistance (AMR). However, the dynamics of AMR transfer through bacterial populations and its direct impact on human disease is poorly elucidated. Here, we study parallel epidemic emergences of multiple Shigella species, a priority AMR organism, in men who have sex with men to gain insight into AMR emergence...
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