Genetic and phenotypic analysis of the virulence plasmid of a non-Shigatoxigenic enteroaggregative Escherichia coli O104:H4 outbreak strain.

doi:10.1099/mic.0.001550

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Article

Genetic and phenotypic analysis of the virulence plasmid of a non-Shigatoxigenic enteroaggregative Escherichia coli O104:H4 outbreak strain.

Microbiology (Reading, England) - 1 Mar 2025

Whelan Rachel, Cyganek Martyna, Oxley Charlotte L, Dickins Benjamin, Thomas Jonathan C, McVicker Gareth

Abstract excerpt

Enteroaggregative Escherichia coli O104:H4 is best known for causing a worldwide outbreak in 2011 due to the acquisition of a Shiga-like toxin alongside traditional enteroaggregative virulence traits; however, whilst the 2011 outbreak strain has been well studied, the virulence plasmid of O104:H4 has been subjected to far less experimental analysis. In this paper, we analyse the genetic and phenotypic...

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Topics

Plasmids
Escherichia coli Infections
Virulence
Humans
Disease Outbreaks
Escherichia coli O104

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Phenotype

Escherichia coli Proteins

Virulence Factors

United Kingdom

Toxin-Antitoxin Systems

Bacterial Adhesion

Biofilms

Source

Open in PubMed Open full text

Identifiers

PMID: 40146611
DOI: 10.1099/mic.0.001550
PMCID: PMC11950199

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