Article
FOXP3 and TGF-β gene polymorphisms in allergic rhinitis.
Iranian journal of immunology : IJI - 1 Dec 2011
Hassannia Hadi, Abediankenari Saeid, Ghaffari Javad
Abstract excerpt
BACKGROUND: Regulatory CD4+ T (Treg) cells are effective in maintaining immune tolerance. OBJECTIVE: To investigate single nucleotide polymorphisms (SNPs) of Transforming Growth Factor β-1 (TGF-β1) and Forkhead Box Protein 3 (FOXP3) genes in Iranian patients with allergic rhinitis (AR). METHODS: Variations at codons 10 and 25 of TGF-β1 and FOXP3 at positions -3279 A>C and -924 A>G were evaluated in AR patients...
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