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Article

Phenotype Characterization of a Mice Genetic Model of Absolute Blindness.

International journal of molecular sciences - 24 Jul 2022

Milla-Navarro Santiago, Pazo-González Mateo, Germain Francisco, de la Villa Pedro

Abstract excerpt

Recent technological development requires new approaches to address the problem of blindness. Such approaches need to be able to ensure that no cells with photosensitive capability remain in the retina. The presented model, Opn4-/- × Pde6brd10/rd10 (O×Rd) double mutant murine, is a combination of a mutation in the Pde6b gene (photoreceptor degeneration) together with a deletion of the Opn4 gene (responsible for...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 35897728
DOI: 10.3390/ijms23158152
PMCID: PMC9331777

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