Article
Electroretinography as a screening method for mutations causing retinal dysfunction in mice.
Investigative ophthalmology & visual science - 1 Feb 2004
Dalke Claudia, Löster Jana, Fuchs Helmut, Gailus-Durner Valerie, Soewarto Dian, Favor Jack, Neuhäuser-Klaus Angelika, Pretsch Walter, Gekeler Florian, Shinoda Kei, Zrenner Eberhart, Meitinger Thomas, Hrabé de Angelis Martin, Graw Jochen
Abstract excerpt
PURPOSE: To detect mice with hereditary retinal impairment, a high-throughput electroretinography (ERG) screening system was established. METHOD: Mice from eight different strains without known retinal disorders (102, 129/SvJ, AKR, C57BL/6J, C57BL/6JIco, CBA/CaJ, and DBA/2NCrlBR) and one control strain with retinal degeneration (C3HeB/FeJ) were fixed on a specially constructed sled, ERG electrodes were placed on...
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