Article
[Advance in studies on regulatory mechanism of phenotype polarization of macrophages and intervention with traditional Chinese medicines].
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica - 1 Jan 2015
Wang Yuan-lai, Bian Ka, Zhang Dan-dan
Abstract excerpt
Macrophages are heterogeneous and diversified, and can be polarized into different phenotypes in various microenvironments and physiological or pathological conditions. Major macrophage subpopulations including classically activated(M1) and alternatively activated(M2) macrophages, which represent different surface receptors, secret different cytokines and chemokines, are regulated by different signal paths of...
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