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Article

Predicting the herbal medicine triggering innate anti-tumor immunity from a system pharmacology perspective.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie - 1 Nov 2021

Xiao Yue, Zhang Lulu, Zhu Jinglin, Zhang Yuru, Yang Ruijie, Yan Jiangna, Huang Ruifei, Zheng Chunli, Xiao Wei, Huang Chao, Wang Yonghua

Abstract excerpt

Although the main focus of immuno-oncology has been manipulating the adaptive immune system, tumor associated macrophages (TAMs) are the main infiltrating component in the tumor microenvironment (TME) and play a critical role in cancer progression. TAMs are mainly divided into two different subtypes: macrophages with antitumor or killing activity are called M1 while tumor-promoting or healing macrophages are...

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PMID: 34560533
DOI: 10.1016/j.biopha.2021.112105

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