Article
Jiedu Xiaozheng Yin Inhibits the Progression of Colitis Associated Colorectal Cancer by Stimulating Macrophage Polarization Towards an M1 Phenotype via the TLR4 Pathway.
Integrative cancer therapies - 1 Jan 2000
Liu Haiqin, Yan Shuo, Yang Ruiming, Huang Caidi, Guo Kangyue, Wang Shi, Huang Yunmei, Shen Dongyi, Lin Ying, Cao Zhiyun, Zhong Hangyan, Lin Jiumao, Chen Xuzheng
Abstract excerpt
To investigate the effect of Jiedu Xiaozheng Yin (JXY) on the polarization of macrophages in colitis-associated colon cancer (CAC). An orthotopic model of CAC was established to monitor changes in the pathological state of mice. Colon length, number of colon tumors were recorded, and indices for liver, spleen, and thymus were calculated. Hematoxylin and eosin (H&E) staining was employed to observe intestinal...
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