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Risk-reducing surgery in unaffected individuals receiving cancer genetic testing in an integrated health care system.

Cancer - 15 Aug 2022

Knerr Sarah, Guo Boya, Mittendorf Kathleen F, Feigelson Heather Spencer, Gilmore Marian J, Jarvik Gail P, Kauffman Tia L, Keast Erin, Lynch Frances L, Muessig Kristin R, Okuyama Sonia, Veenstra David L, Zepp Jamilyn M, Goddard Katrina A B, Devine Beth

Abstract excerpt

BACKGROUND: Germline genetic testing enables primary cancer prevention, including through prophylactic surgery. We examined risk-reducing surgeries in unaffected individuals tested for hereditary cancer susceptibly between 2010 and 2018 in the Kaiser Permanente Northwest health system. METHODS: We used an internal genetic testing database to create a cohort of individuals who received tests including one or more...

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Identifiers

PMID: 35679147
DOI: 10.1002/cncr.34349
PMCID: PMC9308746

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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