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<scp>BRD4</scp>and<scp>MYC</scp>: power couple in transcription and disease

22 Jul 2022

Abstract excerpt

The MYC proto-oncogene and BRD4, a BET family protein, are two cardinal proteins that have a broad influence in cell biology and disease. Both proteins are expressed ubiquitously in mammalian cells and play central roles in controlling growth, development, stress responses and metabolic function. As chromatin and transcriptional regulators, they play a critical role in regulating the expression of a burgeoning...

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PMID: 35866356
DOI: 10.1111/febs.16580

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