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Screening of BRCA1/2 variants in Mauritanian breast cancer patients.

BMC cancer - 20 Jul 2022

Brahim Selma Mohamed, Zein Ekht Elbenina, Bonnet Crystel, Hamed Cheikh Tijani, Salame Malak, Zein Mohamed Vall, Khyatti Meriem, Tolba Ahmedou, Houmeida Ahmed

Abstract excerpt

BACKGROUND AND STUDY AIM: Carrying a pathogenic BRCA1/2 variant increases greatly young women's risk of developing breast cancer (BC). This study aimed to provide the first genetic data on BC in Mauritania. METHODS: Using NGS based screening; we searched for BRCA1/2 variants in DNA samples from 137 patients diagnosed for hereditary BC. RESULTS: We identified 16 pathogenic or likely pathogenic (PV) variants...

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Identifiers

PMID: 35858847
DOI: 10.1186/s12885-022-09903-8
PMCID: PMC9301826

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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