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BRCA1 and BRCA2 germline variants in breast cancer patients from the Republic of Macedonia.

Breast cancer research and treatment - 1 Apr 2018

Jakimovska Milena, Maleva Kostovska Ivana, Popovska-Jankovic Katerina, Kubelka-Sabit Katerina, Karadjozov Mitko, Stojanovska Liljana, Arsovski Andreja, Smichkoska Snezhana, Lazarova Emilija, Jakimovska Dimitrovska Maja, Plaseska-Karanfilska Dijana

Abstract excerpt

PURPOSE: We aimed to establish the spectrum of BRCA1/2 mutations among the breast cancer (BC) patients from the Republic of Macedonia. METHODS: We used targeted next-generation sequencing (NGS), Sanger DNA sequencing, and multiplex ligation probe amplification analysis (MLPA) to search for point mutations and deletions/duplications involving BRCA1 and BRCA2-coding regions. RESULTS: We have analyzed a total of 313...

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PMID: 29335924
DOI: 10.1007/s10549-017-4642-5

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BRCA1
BRCA2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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