Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Design and Application of Multiplex PCR Seq for the Detection of Somatic Mutations Associated with Myeloid Malignancies.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2017

Park Naomi, Vassiliou George

Abstract excerpt

Targeted sequencing, in which only a selected set of genomic loci are sequenced, enables a much higher coverage of each target than what is obtained using whole genome or exome sequencing. Multiplex PCR offers a simple and affordable technique for specific capture of target regions and can be easily adapted to generate next-generation sequencing (NGS)-ready amplicons. Here we describe a multiplex PCR (MxPCR)...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Biomarkers, Tumor
Share to High-Throughput Nucleotide Sequencing

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Multiplex Polymerase Chain Reaction

Share to Mutation

Share to Myeloproliferative Disorders

Share to Research Design

Share to Sequence Analysis, DNA

Source

Identifiers

PMID: 28735482
DOI: 10.1007/978-1-4939-7142-8_6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Design and Application of Multiplex PCR Seq for the Detection of Somatic Mutations Associated with Myeloid Malignancies.PMID 28735482Read ↗

Targeted Next-Generation Sequencing of Acute Leukemia.Semantic proximity Read ↗

Multiplex PCR for the Rapid Diagnosis of Myeloproliferative Neoplasms.Semantic proximity Read ↗

Next-generation sequencing-based multigene mutational screening for acute myeloid leukemia using MiSeq: applicability for diagnostics and disease monitoring.Semantic proximity Read ↗

Successful classification of clinical pediatric leukemia genetic subtypes via structural variant detection using HiFi long-read sequencingSemantic proximity Read ↗

Targeted next generation sequencing of clinically significant gene mutations and translocations in leukemia.Semantic proximity Read ↗

Genotyping of 25 leukemia-associated genes in a single work flow by next-generation sequencing technology with low amounts of input template DNA.Semantic proximity Read ↗

Target variant detection in leukemia using unaligned RNA-Seq readsSemantic proximity Read ↗

MIPP-Seq: ultra-sensitive rapid detection and validation of low-frequency mosaic mutations.Semantic proximity Read ↗

Comprehensive Analysis of Disease-Related Genes in Chronic Lymphocytic Leukemia by Multiplex PCR-Based Next Generation Sequencing.Semantic proximity Read ↗

Multiplex accurate sensitive quantitation (MASQ) with application to minimal residual disease in acute myeloid leukemia.Semantic proximity Read ↗

Targeted Next-Generation Sequencing for Detecting MLL Gene Fusions in LeukemiaSemantic proximity Read ↗

Targeted ultradeep next-generation sequencing as a method for KIT D816V mutation analysis in mastocytosis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.