Article
Updated Genome-Wide Association Study of Intracranial Aneurysms by Genotype Correction and Imputation in Koreans.
World neurosurgery - 1 Oct 2022
Hong Eun Pyo, Kim Bong Jun, Youn Dong Hyuk, Lee Jae Jun, Jeon Hong Jun, Choi Hyuk Jai, Cho Yong Jun, Jeon Jin Pyeong
Abstract excerpt
OBJECTIVE: Compared to European, Japanese, and Chinese populations, genetic studies on intracranial aneurysms (IAs) in Koreans are lacking. We conducted an updated genome-wide association study (GWAS) to more accurately identify candidate variations predicting IA by genotype correction and imputation than in the first Korean GWAS. METHODS: We performed a high-throughput imputation of single-nucleotide...
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