Article
FOXP3 Gene Variants in Patients with Systemic Lupus Erythematosus: Association with Disease Susceptibility in Men and Relationship with Abortion in Women.
Iranian journal of immunology : IJI - 1 Jun 2022
Heydarinejad Paria, Gholijani Nasser, Habibagahi Zahra, Malekmakan Mohammad Reza, Amirghofran Zahra
Abstract excerpt
BACKGROUND: FOXP3, an important transcription factor of regulatory T cells has shown a contribution to the development of various autoimmune diseases. OBJECTIVES: To investigate the influence of FOXP3 polymorphisms (rs3761548 and rs2294021) on systemic lupus erythematosus (SLE) susceptibility and patients' characteristics. METHODS: Genotyping was performed on 265 patients with SLE and 404 healthy controls using...
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