Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Alternative pathway for dopamine production by acetogenic gut bacteria that O-Demethylate 3-Methoxytyramine, a metabolite of catechol O-Methyltransferase

23 Jun 2022

Abstract excerpt

AIMS: The gut microbiota modulates dopamine levels in vivo, but the bacteria and biochemical processes responsible remain incompletely characterized. A potential precursor of bacterial dopamine production is 3-methoxytyramine (3MT); 3MT is produced when dopamine is O-methylated by host catechol O-methyltransferase (COMT), thereby attenuating dopamine levels. This study aimed to identify whether gut bacteria are...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cannabis and Cannabinoid Research
Share to Folate and B Vitamins Research
Share to Gut microbiota and health

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 35737746
DOI: 10.1111/jam.15682

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Alternative pathway for dopamine production by acetogenic gut bacteria that O-Demethylate 3-Methoxytyramine, a metabolite of catechol O-MethyltransferasePMID 35737746Read ↗

Trimethylamine and Trimethylamine N-Oxide, a Flavin-Containing Monooxygenase 3 (FMO3)-Mediated Host-Microbiome Metabolic Axis Implicated in Health and DiseaseSemantic proximity Read ↗

Relationship Between Gut Bacteria and Levodopa MetabolismSemantic proximity Read ↗

Elucidation of an anaerobic pathway for metabolism of L-carnitine-derived γ-butyrobetaine to trimethylamine in human gut bacteriaSemantic proximity Read ↗

Trimethylamine- N -oxide formation, the bacterial taxa involved and intervention strategies to reduce its concentration in the human bodySemantic proximity Read ↗

Potential TMA-Producing Bacteria Are Ubiquitously Found in MammaliaSemantic proximity Read ↗

A small, polyphyletic group of Firmicutes synthesizes trimethylamine from l ‐carnitineSemantic proximity Read ↗

Discovery and Characterization of Gut Microbiota Decarboxylases that Can Produce the Neurotransmitter TryptamineSemantic proximity Read ↗

Uncovering the trimethylamine-producing bacteria of the human gut microbiotaSemantic proximity Read ↗

The Relationship between Choline Bioavailability from Diet, Intestinal Microbiota Composition, and Its Modulation of Human Diseases.Semantic proximity Read ↗

Trimethylamine modulates dauer formation, neurodegeneration, and lifespan through tyra-3/daf-11 signaling in Caenorhabditis elegans.Semantic proximity Read ↗

Characterization of TMAO productivity from carnitine challenge facilitates personalized nutrition and microbiome signatures discoverySemantic proximity Read ↗

Enterococcus hirae QT4713-derived dopamine ameliorates intestinal inflammation and MPTP-induced Parkinson’s disease in miceSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.