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Article

A comprehensive analysis of the microbiota composition and host driver gene mutations in colorectal cancer.

Investigational new drugs - 1 Oct 2022

Yuan Danping, Tao Yong, Wang Haoyi, Wang Jiawei, Cao Yuepeng, Cao Wen, Pan Shou, Yu Zhaonan

Abstract excerpt

Studies of both, microbiota and target therapy associated with gene mutations in colorectal cancer, (CRC) have attracted increasing attention. However, only a few of them analyzed the combined effects on CRC. we analyzed differences in intestinal microbiota of 44 colorectal cancer patients and 20 healthy controls (HC) using 16S rRNA gene sequencing of fecal samples. For 39 of the CRC patients, targeted Next...

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Source

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Identifiers

PMID: 35727391
DOI: 10.1007/s10637-022-01263-1
PMCID: PMC9395472

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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