Article

Colorectal cancer mutational profiles correlate with defined microbial communities in the tumor microenvironment

2016-12-01

Abstract excerpt

Variation in the gut microbiome has been linked to colorectal cancer (CRC), as well as to host genetic variation. However, we do not know whether, in addition to baseline host genetics, somatic mutational profiles in CRC tumors interact with the surrounding tumor microbiome, and if so, whether these changes can be used to understand microbe-host interactions with potential functional biological relevance. Here, we...

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Literature Corpus work: a3b13ea2-b3b4-50e4-861d-f4254187a423
DOI: 10.1101/090795

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