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Article

Gut microbiome associated with APC gene mutation in patients with intestinal adenomatous polyps.

International journal of biological sciences - 1 Jan 2020

Liang Siyuan, Mao Yan, Liao Ming, Xu Yansong, Chen Yingchun, Huang Xiaoliang, Wei Chuangyi, Wu Changtao, Wang Qiuyan, Pan Xiaoyan, Tang Weizhong

Abstract excerpt

Background: The 'adenoma-carcinoma sequence' is a well-recognized model of colorectal cancer (CRC) development. However, the interaction between gut microbiota and genetic variation in the initiation of CRC is not clear. Our study attempts to demonstrate the relationship between gut microbiota and host genetics in patients with intestinal adenomatous polyps. Method: The entire exon region of the APC gene was...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 31892851
DOI: 10.7150/ijbs.37399
PMCID: PMC6930378

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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