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Profiling of host genetic alterations and intra-tumor microbiomes in colorectal cancer

1 Jan 2021

Abstract excerpt

Some bacteria are symbiotic in tumor tissues, and metabolites of several bacterial species have been found to cause DNA damage. However, to date, the association between bacteria and host genetic alterations in colorectal cancer (CRC) has not been fully investigated. We evaluated the association between the intra-tumor microbiome and host genetic alterations in 29 Japanese CRC patients. The tumor and non-tumor...

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PMID: 34188781
DOI: 10.1016/j.csbj.2021.05.049

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