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Article

Colorectal cancer-associated T cell receptor repertoire abnormalities are linked to gut microbiome shifts and somatic cell mutations.

Gut microbes - 1 Dec 2023

Cao Yuan, Wang Jifeng, Hou Weiliang, Ding Yanqiang, Zhu Yefei, Zheng Jiayi, Huang Qiongyi, Cao Zhan, Xie Ruting, Wei Qing, Qin Huanlong

Abstract excerpt

As with many diseases, tumor formation in colorectal cancer (CRC) is multifactorial and involves immune, environmental factors and various genetics that contribute to disease development. Accumulating evidence suggests that the gut microbiome is linked to the occurrence and development of CRC, and these microorganisms are important for immune maturation. However, a systematic perspective integrating microbial...

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Identifiers

PMID: 37795995
DOI: 10.1080/19490976.2023.2263934
PMCID: PMC10557533

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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