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Article

The Impact of BRCA1- and BRCA2 Mutations on Ovarian Reserve Status.

Reproductive sciences (Thousand Oaks, Calif.) - 1 Jan 2023

C E Drechsel Katja, C van Tilborg Theodora, J C Eijkemans Marinus, G W M Lentjes Eef, Irene Homminga, Mariette Goddijn, J T van Golde Ron, Willem Verpoest, D Lichtenbelt Klaske, J M Broekmans Frank, M E Bos Anna

Abstract excerpt

This study aimed to investigate whether female BRCA1- and BRCA2 mutation carriers have a reduced ovarian reserve status, based on serum anti-Mullerian hormone (AMH) levels, antral follicle count (AFC) and ovarian response to ovarian hyperstimulation. A prospective, multinational cohort study was performed between October 2014 and December 2019. Normo-ovulatory women, aged 18-41 years old, applying for their first...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 35705781
DOI: 10.1007/s43032-022-00997-w
PMCID: PMC9810575

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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